De Groot pursues Ebola research

As world health experts work to contain Ebola in West Africa, URI scientist Dr. Annie S. De Groot is working to develop a vaccine for the disease. More

To continue reading this article, please do one of the following.



health care

De Groot pursues Ebola research

PBN FILE PHOTO/RUPERT WHITELEY
USING EBOLA epitopes, De Groot has demonstrated an immune response in a mouse. While that initial study was limited in scope, she said she is confident she could produce an effective vaccine if her studies were expanded to additional Ebola antigens.
Posted 8/18/14

SOUTH KINGSTOWN – As world health experts work to contain Ebola in West Africa, URI scientist Dr. Annie S. De Groot is working to develop a vaccine for the disease.

De Groot, who is director of the University of Rhode Island Institute for Immunology and Informatics, as well as medical director of Clinica Esperanza in Providence and CEO of biotechnology company EpiVax, has conducted preliminary studies of an Ebola vaccine in collaboration with scientists at the U.S. Army Medical Research Institute of Infectious Diseases.

Using Ebola epitopes, De Groot has demonstrated an immune response in a mouse. While that initial study was limited in scope, she said she is confident she could produce an effective vaccine if her studies were expanded to additional Ebola antigens.

“Not only would this approach be safer than whole-antigen approaches that are currently being explored, but it would be more rapid,” De Groot said.

De Groot has previous experience working on fast-track vaccines with the Army research outfit.

“The key to making an effective Ebola vaccine, I believe, is to trick the immune system into producing robust immune response to Ebola antigens while avoiding any components that might cause adverse effects,” she said. “That’s the best attribute of epitope-based vaccines, which are well-accepted in cancer therapy but have faced unanticipated barriers to entry in infectious diseases.”

Calendar
PBN Hosted
Events

Join PBN for the best networking event and party of the winter - January 15, 2015 - the Book of Lists Party at the Providence Public Library. Reserve your spot by December 31st and get a holiday gift from PBN!
  • Best Places to Work
    Enrollment is now open for the 7th annual Best Places to Work program. Winners w ...
  • Manufacturing Awards
    Applications are now being accepted for the 2nd Annual Manufacturing Awards. Dea ...
Advertisement
Purchase Data
Book of Lists
Lists
Book of Lists cover
PBN's annual Book of Lists has been an essential resource for the local business community for almost 30 years. The Book of Lists features a wealth of company rankings from a variety of fields and industries, including banking, health care, real estate, law, hospitality, education, not-for-profits, technology and many more.
Data icons
Data can be purchased as single lists, in either Excel or PDF format; the entire database of the published book, in Excel format; or a printed copy of the Book of Lists.
  • Purchase an e-File of a single list
  •  
  • Purchase an e-File of the entire Book of Lists database
  •  
  • Purchase a printed copy of the Book of Lists
  •  
    National
    Local
    Latest News
    Advertisement